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Mass spectrometry analysis services for oligonucleotides, peptides, proteins, and bioconjugates

Mass spectrometry characterization support

Mass spectrometry is commonly used to confirm molecular weight, evaluate sample integrity, verify modifications, and characterize biological compounds. Bio-Synthesis utilizes mass spectrometry analysis to support peptide, oligonucleotide, protein, and conjugate characterization workflows.

Applications may include molecular weight confirmation, conjugation verification, impurity assessment, peptide characterization, oligonucleotide analysis, and analytical troubleshooting.

Sample types and characterization support

Oligonucleotides

  • Molecular weight confirmation
  • Modified oligonucleotide analysis
  • Conjugate verification
  • Impurity assessment

Peptides & Proteins

  • Peptide mass confirmation
  • Protein characterization
  • Modification analysis
  • Identity verification

Bioconjugates

  • Peptide-oligo conjugates
  • Labeled biomolecules
  • Linker verification
  • Conjugation confirmation

Preparing samples for mass spectrometry analysis

Submission Recommendations

  • Submit purified material whenever possible
  • Provide expected molecular weight and concentration
  • Include buffer or solvent information
  • Clearly identify modified or conjugated samples
  • Label all submitted materials clearly

Important Notes

  • Avoid excessive salt or detergent concentrations
  • Ship temperature-sensitive samples appropriately
  • Low-salt or desalted samples are preferred
  • Additional cleanup may be recommended
  • Contact us for unusual sample types

Need analytical characterization support?

Please contact Bio-Synthesis to discuss sample compatibility and project requirements.

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Why Choose Bio-Synthesis

Trusted by biotech leaders worldwide for over 45+ years of delivering high quality, fast and scalable synthetic biology solutions.