40+ years of excellence in custom synthesis and bioconjugation services.
Calculators, design tools, and educational content to support your research.
Custom research-grade oligonucleotide synthesis for advanced molecular biology, genomics, and diagnostic research workflows.
OligoLS™ supports molecular biology, assay development, discovery research, and diagnostic development workflows where sequence accuracy, modification flexibility, purification strategy, and analytical confidence matter.
Custom primers, probes, fluorescent reporters, quenchers, and assay-ready oligos for amplification and quantitative detection workflows.
Adapters, indexes, barcodes, capture probes, and custom oligos supporting sequencing library preparation and targeted analysis.
Guide RNAs, donor templates, modified oligos, and design-supporting synthesis options for genome editing and functional studies.
FISH probes, molecular beacons, labeled probes, dual-labeled probes, and specialty oligos for imaging and detection workflows.
Research-use oligos for assay development, validation studies, pathogen detection, genetic testing research, and biomarker analysis.
RNA oligos, modified RNA, siRNA research tools, antisense research oligos, and constructs for gene expression studies.
Biotin, fluorophore, linker, thiol, amino, lipid, peptide, and other conjugation-ready oligos for specialized applications.
Custom oligo designs for synthetic biology, biomarker research, target validation, screening, and exploratory molecular biology workflows.
OligoLS™ is designed for research teams that need dependable oligonucleotide synthesis, flexible chemistry options, and practical technical support for assay-driven molecular biology workflows.
Feature
Oligos can be specified around the actual research workflow, not only sequence and scale.
Benefit
Better alignment between synthesis, purification, modification, and application can reduce troubleshooting during downstream experiments.
Advantage
Bio-Synthesis supports modified, labeled, conjugated, and difficult oligo designs that basic catalog-style ordering systems may not handle well.
Bio-Synthesis supports standard and specialty oligonucleotide modifications to help researchers design oligos for detection, binding, stability, conjugation, imaging, sequencing, and functional studies.
Research-grade oligos can require different purity, yield, and analytical strategies depending on application, length, modification, and assay sensitivity.
OligoLS™ supports researchers with flexible synthesis, modification, purification, and analytical workflows designed for advanced molecular biology applications.
Bio-Synthesis combines research-use oligonucleotide synthesis with deeper custom chemistry capabilities, helping scientists move from routine primer ordering to more complex modified, labeled, conjugated, and assay-critical oligo designs.
Long-standing custom synthesis experience supporting biotechnology, pharmaceutical, diagnostic, and research organizations.
Quality-focused workflows for research-use oligonucleotide synthesis, documentation, and customer support.
Support for standard, modified, labeled, conjugated, and assay-critical oligonucleotide designs.
Purification and analytical options matched to routine primers, sensitive probes, modified oligos, and demanding assay systems.
Common questions about OligoLS™ research-use oligos, modification options, purification choices, and when to request technical guidance.
Related Services
Many oligonucleotide research programs also require molecular biology support, bioconjugation services, or downstream therapeutic development services. Explore related capabilities across the Bio-Synthesis platform.
Support for cloning, gene synthesis, mutagenesis, sequencing support, assay development, and recombinant DNA workflows.
Custom oligo conjugates, fluorescent labeling, linker strategies, carrier proteins, peptide conjugates, and specialty conjugation workflows.
For programs moving beyond RUO, Bio-Synthesis can support scale-up, chemistry development, analytical strategy, and development planning.
Discuss modifications, purification strategies, long oligos, probes, or application-specific synthesis requirements with our scientific team.
Submit sequence, scale, modification, purification, and delivery requirements for project review.
Trusted by biotech leaders worldwide for over 45 years of delivering high-quality, fast, and scalable synthetic biology solutions.