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BSI explicit commitment to long-term continuous R&D development has developed a cost-effective method of synthesis for your PNA at multiple size and scale with wide range of modifications with SPEED, Quality and Flexibility. From simple PNA synthesis to PNA conjugations or oligo chimeras. Our team of experienced chemists are available to help you arrive at the best design and synthesis strategies to meet your research goals.

Feature

	FREE PNA design and self complimentary check
	Multi-scale synthesis (nmoles to mmoles)
	Wide selection of modifications
	Comprehensive QC analyses by HPLC and MALDI-TOP mass spectrometry
	Explicit commitment to long-term continuous improvements and cost-competitiveness
	Fast delivery with high throughput capacities

Unmodified PNA
Refer to PNA with no labels or fluorophores attached to it, but they have the N termini free or blocked. These options are:
	Unmodified PNA	Unmodified PNA with Options*
	Free Amine The PNA molecule contains a free primary amine at the N terminus. This free primary amine permits users to introduce modifications.			Addition of Lysine The addition of one or more lysine to either N or C-terminus of a PNA molecule provides a positive charge into the PNA and increases water solubility and cellular uptake.
	Acetylated: The PNA molecule contain an acetyl group at the N-terminus can blocks any further reactivity at the N terminus.			Addition of Solubility Enhancer Solubility enhancer which do not bring any charge to molecular but enhances solubility can be added at the C or N terminus.
	Alkylation The PNA molecule contains an alkyl group at the N terminus.			Linker Addition O-Linker can also be used to increase the solubility of PNA in water. Normally, linkers are added to the N-terminus, where a user can attach its own label.

PNA Modifications
For target detection, in situ detection or other applications, we can attach your PNA molecule with a variety of fluorophores including but not limited to the list below. BSI continually developing the incorporation of labelings and modifications. If a modifications or labelings not listed below, please inquire. It may be available as a product under development or we may be able to add it to our list of R&D projects.
	Modified PNA		Modified PNA with Options*
	HEX, TET, JOE Texas Red, Biotin, FITC Dansyl, Digoxigenin, Cy3 and Cy5.			Linkage at the N-Terminus, via O-linker (or other)
				Linkage at the C-Terminus, via a Lys/Cys added as the last residue of the PNA sequence.
Please contact us for any other label specific to your needs.

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PNA Synthesis

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Dual Labeled PNA

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