Site Specific and Structure Modifications
With over 20 years of practical peptide synthesis and research experience, we have
developed highly specific expertise with modified and difficult to synthesize peptides.
With a diverse range of modifications available for peptides, BSI routinely meets
our clients' specifications with unusual, custom made peptides. To deliver top quality
solutions, BSI utilizes a wide range of chemistries including solid and solution
phase methodology, along with tactical protecting strategies such as Fmoc, t-Boc
and Cbz. These specialized methodologies enable us great versatility for site-specific
modifications such as biotinylation, acetylation,
, amidation, phosphoryation,
fatty acid attachment and more.
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Also available: Fluorescence Labels, Stable Isotopes, Conjugations, Unusual Amino
Acids.
Structure Modifications
Peptide Nucleic Acid Synthesis (PNA) is a custom made solution offered by Bio-Synthesis.
This PNA is an analogue of DNA in which the backbone is a "peptide-like" structure
rather than a sugar. The PNA mimics the behavior of DNA and binds complementary
nucleic acid strands. By utilizing the high-affinity binding and sequence specificity
of engineered peptide nucleic acids to improve gene targeting and reduce non-specific
interactions, this is becoming a powerful tool. Bio-Synthesis's custom PSEUDOPEPTIDE
nucleic acid synthesis services provide a unique alternative for oligonucleotide
probes.
Site Specific Modifications... to explore more, click your selection.
All custom labeled peptides include:
MALDI-TOF Mass Spectrometry
*Optional services: Amino acid Analysis and Sequencing