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  Custom LNA  (Lock Nucleic Acid) -  Modifications

5' Modifications 3' Modifications

Phosphorothioates

Others


We are committed to long-term continuous improvement and developing the incorporation of modifications and minor bases. If a modification that you desire is not listed below, Please contact us. It may be available as a product under development or we may be able to add it to our list of R&D projects. Your feedback will assist BioSynthesis in ensuring that the modifications which we offer best address our customers' needs.

Modification is an additional charge to the synthesis.

3' Modifications
Guaranteed Yield (OD)  5-10 15-20 35-40
Synthesis Scales: 0.2 µmol 0.4 µmol 1.0 µmol
3'-Biotin $140.00 $160.00 $200.00
3'-Inverted abasic $50.00 $60.00 $75.00
3'-Inverted deoxythymidine $50.00 $60.00 $75.00
3'-Puromycin $50.00 $60.00 $75.00
3' Terminal dideoxy-cytidine $75.00 $85.00 $110.00
3'-TAMRA $190.00 $225.00 $275.00
3'-Fluorescein $90.00 $100.00 $125.00
3' Terminal deoxy-guanosine $75.00 $85.00 $110.00
3'-LC Biotin $140.00 $160.00 $200.00
3'-LC LC Biotin $140.00 $160.00 $200.00
3'-Cholesterol $140.00 $160.00 $200.00
 3'-Amino Modifier (6 atom) $50.00 $60.00 $75.00
 3'-DY547 (Cy3T alternate) $290.00 $350.00 $425.00
 3'-DY647 (Cy3T alternate) $290.00 $350.00 $425.00

Phosphorothioate Modifications
Guaranteed Yield (OD)  5-10 15-20 35-40
Synthesis Scales: 0.2 µmol 0.4 µmol 1.0 µmol
Phosphorothioate $25.00 $28.00 $30.00

Other Modifications
Guaranteed Yield (OD)  5-10 15-20 35-40
Synthesis Scales: 0.2 µmol 0.4 µmol 1.0 µmol
18-Atom spacer (Hexaethylene glycol) $30.00 $40.00 $55.00
3-Carbon linker $30.00 $40.00 $55.00
9-Atom spacer $30.00 $40.00 $55.00
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