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Custom LNA Synthesis
 
 
 

Custom LNA

  (Lock Nucleic Acid) - 
Modifications


5' Modifications 3' Modifications

Phosphorothioates

Others

We are committed to long-term continuous improvement and developing the incorporation of modifications and minor bases. If a modification that you desire is not listed below, please contact us. It may be available as a product under development or we may be able to add it to our list of R&D projects. Your feedback will assist Bio-Synthesis in ensuring that the modifications which we offer best address our customers' needs.

Each modification is an additional charge to the synthesis.

3' Modifications
Guaranteed Yield (OD)  5-10 15-20 35-40
Synthesis Scales: 0.2 µmol 0.4 µmol 1.0 µmol
3'-Biotin $140.00 $160.00 $200.00
3'-Inverted abasic $50.00 $60.00 $75.00
3'-Inverted deoxythymidine $50.00 $60.00 $75.00
3'-Puromycin $50.00 $60.00 $75.00
3' Terminal dideoxy-cytidine $75.00 $85.00 $110.00
3'-TAMRA $190.00 $225.00 $275.00
3'-Fluorescein $90.00 $100.00 $125.00
3' Terminal deoxy-guanosine $75.00 $85.00 $110.00
3'-LC Biotin $140.00 $160.00 $200.00
3'-LC LC Biotin $140.00 $160.00 $200.00
3'-Cholesterol $140.00 $160.00 $200.00
 3'-Amino Modifier (6 atom) $50.00 $60.00 $75.00
 3'-DY547 (Cy3T alternate) $290.00 $350.00 $425.00
 3'-DY647 (Cy3T alternate) $290.00 $350.00 $425.00

Phosphorothioate Modifications
Guaranteed Yield (OD)  5-10 15-20 35-40
Synthesis Scales: 0.2 µmol 0.4 µmol 1.0 µmol
Phosphorothioate $25.00 $28.00 $30.00

Other Modifications
Guaranteed Yield (OD)  5-10 15-20 35-40
Synthesis Scales: 0.2 µmol 0.4 µmol 1.0 µmol
18-Atom spacer (Hexaethylene glycol) $30.00 $40.00 $55.00
3-Carbon linker $30.00 $40.00 $55.00
9-Atom spacer $30.00 $40.00 $55.00
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Custom Synthesis