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Custom LNA (Lock Nucleic Acid) Synthesis and Purifications

BSI offer LNA* oligos synthesis with different versatilities. LNA* oligo can be order with a mixture of DNA, RNA, nucleic acid analogues and different synthesis backbone and modifications.

All of our LNA oligo synthesis are:

NO Setup Fee

Deprotected, Desalted and Ready to Use

QC by Mass Spectrometry MALDI-TOF, HPLC or PAGE

Guaranteed Yields and Turnaround

Antisense Oligonucleotides (10-45 mers)

Quality Deprotected/Desalted

Quantity 5 OD 15 OD 45 OD 4 mgs 8 mgs

Synthesis Scales 100nmole 250 µmole 1 µmole 5 µmole 10 µmole

RNA $5.50 $7.00 $16.00 $55.00 $105.00

2'-OMe $7.50 $12.00 $18.00 $80.00 $150.00

LNA (Lock Nucleic Acid)* $30.00 $35.00 $50.00 $200.00 $375.00

Annealing of Complementary Oligos $35.00 $35.00 $50.00 $250.00 $250.00

Large-Scale LNA Synthesis, are now available from 10 micromoles up to two grams! Call Technical Support at 800-227-0627 or write to us at biosyn@biosyn.com for more information.

A minimum charge of $250 applies for LNA oligo <10 bases and yield may also vary depending on the sequence.

Purifications

RNase-Free HPLC PAGE*

Quantity 1 OD 2 OD 5 OD 10 OD 1 OD

Synthesis Scale 100 nmole 0.2 µmole 0.4 µmole 1 µmole 0.2 µmole

$65.00 $65.00 $100.00 $150.00 $150.00

*PAGE purification only available for 0.2 µmole or larger synthesis scale.

Service Overviews

LNA Synthesis

LNA Modifications

Dual Labeled LNA

LNA Conjugations

LNA Oligo Chimeras

Resources

*License Agreement: Locked-nucleic Acid (LNA) phosphoramidites are protected by EP Pat No. 1013661, US Pat No. 6,268,490 and foreign applications and patents owned by Exiqon A/S. Products are made and sold under a license from Exiqon A/S. Products are for research purposes only. Products may not be used for diagnostic, clinical, commercial or other use, including use in humans. There is no implied license for commercial use, including contract research, with respect to the products and a license must be obtained directly from Exiqon A/S for such use."

The most trusted name in Quality Custom Synthesis.