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BSI offers DNA base synthesis in phosphodiester, phosphorothioate and methylphosphonate backbones. We offer an extensive selection of purifications and oligo modifications, such as linkers, spacers, dyes and modified bases. Also available:

As always, every custom oligonucleotide synthesis is: All of our custom oligonucleotide products are:

 
Deprotected, desalted, lyophilized, Ready-2-Use
Quantitated 2x by UV spectrophotometry to provide an accurate measure of yield
QC checked by mass spectrometry
Fast delivery with high throughput capacity
 
Standard DNA (2' Deoxy) Oligonucleotide Synthesis
Linkages Scale Yields Price Restrictions

Phosphodiester (PO)
$7 Minimum - 25 nmole
$10 Minimum - 100, 250 nmole

 

25 nmole 3 ODs $0.35/base
15-45 bases
100 nmole 5 ODs $0.55/base
15-85 bases
250 nmole 15 ODs $0.95/base
15-85 bases
1 µmole 45 ODs $1.95/base
10-120 bases
5 µmole 200 ODs $9.50/base
5-60 bases
10 µmole 400 ODs $15.00/base
5-60 bases
15 µmole 820 ODs $17.50/base
5-60 bases
Phosphorothioate (PS)
$40 Minimum
250 nmole 15 ODs $3.50/bond 10-25 base
1 µmole 45 ODs $5.50/bond 10-25 base
5 µmole 220 ODs $20.00/bond 10-25 base
10 µmole 420 ODs $35.00/bond 10-25 base
15 µmole 620 ODs Inquire 10-25 base
Methylphosphonate (MPN)
$150 minimum
1 µmole 45 ODs $35.00/bond 10-25 base
5 µmole 220 ODs $85.00/bond 10-25 base
10 µmole 420 ODs $125.00/bond 10-25 base
15 µmole 620 ODs Inquire
10-25 bases
  • * PO - Phosphodiester, PS - Phosphothioate, MPN - Methylphosphonate
  • Guarantee yield is for 20 mers or longer, shorter oligos may have fewer ODs

click here for recommended purification and applications!

Unmodified Standard DNA Purifications
Purifications 100 nmol 250 nmol 1 umol 5 umol 10 umol
PAGE $75.00 $75 $135 $635 $965
HPLC $65.00 $65 $120 $280 $395
IE HPLC $65.00 $65 $120 $280 $395
RNase-Free HPLC $125.00 $125 $175 $365 $595
Dual HPLC $145.00 $145 $200 $560 $765
Dual PAGE & HPLC NA $165 $275 $990 $1500
Guarantee is for 20 to 50 bases in length.. Shorter oligos may have fewer ODs.
An additional 1-2 days of turnaround time is required for purifications. 

click here for recommended purification and applications!


Unmodified Standard DNA Purifications Yields
Purifications 100 nmol 250 nmol 1 umol 5 umol 10 umol
PAGE 1 ODs 2 ODs 10 ODs 50 ODs 100 ODs
HPLC 1 ODs 4 ODs 20 ODs 100 ODs 200 ODs
IE HPLC 1 ODs 4 ODs 20 ODs 100 ODs 200 ODs
RNase-Free HPLC 1 ODs 4 ODs 20 ODs 100 ODs 200 ODs
Dual HPLC 1 ODs 2 ODs 10 ODs 50 ODs 100 ODs
Dual PAGE & HPLC 0.5 OD 1 OD 5 ODs 25 ODs 50 ODs
Guarantee is for 20 to 50 bases in length.. Shorter oligos may have fewer ODs.
An additional 1-2 days of turnaround time is required for purifications. 

click here for recommended purification and applications!

 

DNA Synthesis
High-Throughput Oligos
Antisense Oligos
DNA Modifications
Preparative – Analytical Services
Dual Labeled DNA
DNA Conjugations
DNA Marker
Resources
 

The most trusted name in Quality Custom Synthesis