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BIO-SYNTHESIS offers MAPS as an another method for producing
high titer anti-peptide antibodies. This newer concept was introduced to avoid chemically
undefined entity of an antigen-carrier system. The MAP system utilizes a peptidyl
core of three or seven radially branched lysine core to form a backbone for which
the antigen sequences of interest can be built parallel using standard solid-phase
chemistry. The heptalysine core yields the MAP bearing four or eight copies of the
peptide epitope with a resulting three dimensional molecule which has a high molar
ratio of peptide antigen to core molecule, and therefore, does not require the use
of a carrier protein to induce an antibody response. The high molar ratio and
dense packing of multiple copies of the antigenic epitope in a MAP has been shown
to produce strong immunogenic response.
Contact us for details on Multiple Antigen Peptide (MAPS)