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[Gly21] - beta - Amyloid (1 - 40), A21G, Flemish Mutation (13753-005)

[Gly21] - beta - Amyloid (1 - 40), A21G, Flemish Mutation (13753-005)
Sequence (1LC):
DAEFRHDSGYEVHHQKLVFFGEDVGSNKGAIIGLMVGGVV
Sequence (3LC):
NH2 - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Gly - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - COOH
Catalog :
13753-005
Unit:
0.5 mg
Price/Unit:
$728  (For other quantities please Contact Us or call 972-420-8505 (USA) 800-227-0627 (INTL.) or Fax 972.420.0442)
Purity:
>95%
Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This peptide is the mutant form of the b-Amyloid peptide (1-40). The mutation within the coding region of the ß-Amyloid precursor protein (APP) results in substitution of glycine for alanine in this peptide. Presenile dementia is present in a pattern consistent in the family of British origin with the dominant inheritance of Flemish APP mutation. The impact of the point mutation A21G on b-Amyloid structure and dynamics varies from b-Amyloid (1-40) to b-Amyloid (1-42).
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
M.W.:
4315.9 g/mol
Reference/Citations:
  1. Brooks, W. et al. Neurol. 63, 1613 (2004);
  2. Van Nostrand, W. et al. J. Biol. Chem. 276, 32860 (2001);
  3. A. Huet and P. Derreumaux Biophys. J. 91, 3829 (2006).