8-Amino-2'-deoxyguanosine, 8-Amino-dG

8-Amino dA and 8-amino-dG, are 8-amino-puridines that are often used in the study of triplex (triple helix) formation due to the presence of an additional amino group. The 8-amino group is able to form an additional Hoogsteen purine-pyrimidine hydrogen bond, which serves to increase triple helix stability. Studies have shown that triple-helix-forming oligos (TFO) containing 8-amino-dA form stable helices at a neutral pH, instead of under acidic conditions.

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Product Information

 

Product Name:

8-Amino-2'-deoxyguanosine, 8-Amino-dG

Category:

Modified Bases

Modification Code:

[8-Amino-dG]

Chemical Formula:

C10H13N6O6P

Exact Mass:

344.06

Formula Weight:

344.22

Structure:

Purification:

HPLC or PAGE

Delivery Format:

Lyophilized

Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.

Related Products:

8-Amino-2'-deoxyadenosine, 8-Amino-dA

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