Puromycin Oligonucleotide Modification

Bio-Synthsis provides puromycin oligonucleotide modification service by incorporated to the 3' end of RNA and DNA oligos. Pruomycin, an antibiotic that mimics transfer RNA. Puromycin binds in the ribosome's A site, forms a peptide bond with the growing peptide chain, and blocks further peptide elongation. By linking puromycin to mRNA, a peptide-RNA fusion product results from the translation of the message linking the encoding mRNA with its peptide product ¹.

Contact us for Puromycin Modified Oligonucleotide Synthesis Service.

Product Information

 

Product Name:

Puromycin Oligonucleotide Modification

Modification Code:

[Puromycin]

Chemical Formula:

C22H28N7O7P

Exact Mass:

533.18

Formula Weight:

533.48

Structure:

Purification:

HPLC or PAGE

Delivery Format:

Lyophilized

Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.

References/Citations:

1. R.W. Roberts and J.W. Szostak, Proc. Natl. Acad. Sci. USA, 1997, 94, 12297-302.

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