Custom Fluorescent Labeled Peptides
Bio-Synthesis offers a wide variety of fluorescent labeling services,
which includes expert technical advice on the selection of correct fluorescent labels
for your applications. In addition to our usual quality control data sheet, we also
include excitation and emission spectra for each product. While radio labeled peptides
require special handling procedures and are expensive, our extensive range of fluorescent
labeled peptides can be readily introduced during chain assembly or post-synthetically
in a cost effective manner. We have the capability to construct any viable fluorescent
peptide at your request.
Stable isotope labeling is also available!
For additional information, please contact us or send an email to info@biosyn.com
Fluorescent Labeled Peptides
Amine Reactive Labeling from Bio-Synthesis provides a wide variety
of fluorescent labeled peptides. The vast majority of labels are designed for amino
acid labeling. Therefore, peptides can be labeled with an N-terminal free amine,
internal sequence via amino acid side chain such as Lysine or Dap, or at the C-terminus
of the peptide through the side chain of a lysine residue. Use the wavelength spectrum
below to locate the label requirements for your research.
Fluorescent Resonance Energy Transfer (FRET) has been widely used
in various biological applications. Peptide probes incorporating fluorescent donor/non-fluorescent
acceptor combinations have been developed primarily for various detection of proteolysis
and nucleic acid hybridization1,2 , receptor/ligand interactions3,
distribution and transport of lipids4,5, membrane potential sensing6,7,8,
cyclic AMP detection 9-14. BSI has a range of fluorescent labels suitable
for use in FRET peptides.
To explore our FRET label peptides, click here!
Red Labels
- 5-carboxytetramethylrhodamine [5TMR]
- 5.6-carboxytetramethylrhodamine [5(6)TMR]
- 6-carboxytetramethylrhodamine [6TMR]
- Lissamine Rhodamine B [LRhodB]
Green Labels
- 5-carboxyfluoresceine [5FAM]
- 5,6-carboxyfluoresceine [5(6)FAM]
- 6-carboxyfluoresceine [6-FAM]
- Methoxy coumarin acetic acid
Other Fluorescence Labeled Peptide probes also available such as
- FITC/5-FAM (N-Terminal, Y/N Ahx)
- MCA (N-Terminal)
- HYNIC (N-Terminal)
- DTPA (N-Terminal)
- Texas Red
- Bodipy
- Aminocoumarin
- and many others...
If you are interested in using fluorescence peptide but not list in our page, please
Contact us
for a quote.
All custom labeled peptides includes:
- HPLC Analysis
- MALDI-TOP Mass Spectrometry
- Certificate of Analyses
- Optional services: Amino acid Analysis and Sequencing
Also available for Stable Heavy Isotopes,
Unusual Amino Acids