5-Bromo deoxyuridine, a halogenated base can be incorporate at any position withinn an oligonucleotide. This brominated nucleosides are used in crystallography studies of oligonucleotide structure. They are also photolabile and are used for cross-linking studies to probe the structure of protein-DNA complexes in SELEX technique. Antibodies exist to Br-dU and oligonucleotides containing Br-dU can be used as probes.
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-20°C To -70°C Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.
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