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Multiple Antigen Peptide (MAP)
BIO-SYNTHESIS offers MAPS as an another method for producing high titer anti-peptide antibodies. This newer concept was introduced to avoid chemically undefined entity of an antigen-carrier system. The MAP system utilizes a peptidyl core of three or seven radially branched lysine core to form a backbone for which the antigen sequences of interest can be built parallel using standard solid-phase chemistry. The heptalysien core yields the MAP bearing four or eight copies of the peptide epitope with a resulting three dimensional molecule which has a high molar ratio of peptide antigen to core molecule, and therefore, does not requere the use of a carrier protein to induce an antibody response. These high molar ratio and dense packing of multiple copies of the antigenic epitope in a MAP has been shown to product strong immunogenic response1.2
For details on Multiple Antigen Peptide (MAPS), call 800-227-0627 or write to us atbiosyn@biosyn.com.
