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With
over 20 years experience in custom synthesis for the biomedical
research communities, BSI has developed the expertise to deliver
custom synthesized RNA with quality that meets all your RNAi, siRNA,
shRNA and other RNA projects.
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RNA interference (RNAi) |
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RNA
interference (RNAi) is a mechanism that inhibits gene
expression at the stage of translation or by hindering the
transcription of specific genes. RNAi targets include RNA
from viruses and transposons (significant for some forms of
innate immune response), and also plays a role in regulating
development and genome maintenance. Small interfering RNA
strands (siRNA) are key to the RNAi process, and have
complementary nucleotide sequences to the targeted RNA
strand. |
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MicroRNA |
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MicroRNAs (miRNAs)
are genomically encoded non-coding RNAs that help regulate
gene expression, particularly during development.The
phenomenon of RNA interference, broadly defined, includes
the endogenously induced gene silencing effects of miRNAs
as well as silencing triggered by foreign dsRNA. Mature
miRNAs are structurally similar to siRNAs produced from
exogenous dsRNA, but before reaching maturity, miRNAs must
first undergo extensive post-transcription
modificationreaching maturity, miRNAs must first undergo
extensive post-transcriptional modification. |
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