New nucleic acid diagnostic tool with enhanced hybridization and quantification power.
Shivarov et al. published their work using BNA-NC probes allowed for the quantitative and sensitive detection of different mutant alleles. This rapid, easy and reliable diagnostic method is expected to allow the detection of myeloid malignancies. View Video
Bio-Synthesis has been a provider of Peptide Synthesis services to the life science research community since 1984. We offer a complete range of premium quality peptide products ranging from
bulk API polypeptides to high throughput library peptides and peptide array preparation.
We also provide a large number of peptide modifications as well as peptide synthesis
for diagnostic and therapeutic applications. Bio-Synthesis specializes in both,
liquid phase and solid phase fmoc peptide synthesis chemistry. We have a long
standing record in preparing biologically active polypeptides including long, complex
and hydrophobic peptides synthesized to your specifications.
For additional information, please contact us or send an email to firstname.lastname@example.org
Visit our Catalog Peptides page for a full list of our custom peptides
Sequences are analyzed for hydrophobicity at pH 2 and pH 6.8, aggregation potential,
and other known chemistry issues that may arise due to the peptide's amino acid
composition. The customer is notified of any potential issues ahead of time so that
sequence modifications can be made prior to synthesis when possible. Our peptide
design tool provides analysis output for peptide sequences. If specifications of
the order are not achieved, the customer is notified immediately and given advice
for redesigning the sequence or exploring alternative chemistries.
We use liquid phase and solid phase fmoc peptide chemistries, streamlined production
with fully automated instrumentation and a 24 hour support group located in Texas.
We provide comprehensive oversight to ensure the highest standards of peptide quality.
Solid phase synthesis is performed using optimized Fmoc, Boc methodologies
in a state-of-the-art platform for the rapid synthesis of peptide
in large and high throughput quantity. Cleavage of peptides is performed using trifluoroacetic
acid (TFA), hydrogen fluoride (HF), or other appropriate methods. Most of the peptides
are purified by HPLC using reverse phase C4 and C18 columns. Alternative purification
methods (e.g., ion exchange and gel filtration chromatography) are used when needed.
After satisfactory QC, the peptides are purified by preparative reverse phase HPLC,
freeze dried, packaged and dispatched.
Delivery of custom peptides includes MS and HPLC analysis certificate. Additional
analytical data (e.g., sequencing, amino acid analysis) is available upon request.
We offer a variety of options for custom synthesis. From standard micro
to macro high throughput custom peptide arrays and peptide library synthesis to
specialty peptide modifications, ultra long peptides, high quality bulk
API peptides and over 10,000 ready to go catalog peptides.
Custom peptides from micro-gram to multi-gram at various length, purities and modifications.
Delivered in 5-7 days.
Wide spectrum of modifications from simple dye labeling to complex structure modifications.
High-fidelity synthesis of ultra long peptides up to small proteins.
Cross-linking peptides to oligos, antibodies, protein beads, plates, glass and various
High throughput synthesis of a systematic combination of different peptides
Large, cost-effective sets of peptides formatted to your needs
Multi-grams available at affordable prices.
One-stop service from discovery research to cGMP manufacturing
Powerful recombinant peptide technologies for peptides in any scale and length.
Integrated CRO solutions. Providing custom peptides, peptidomimetics and proteins
to the life science communities.
Sample preparation, peptide/ protein characterization, ID, quantification and biomarker
Bio-Synthesis is a leading supplier of bioactive synthetic peptides, enzyme substrates and inhibitors.
Bio-Synthesis offers a broad range of products and services for life science research
Biomarker Discovery, Epitope Validation, Immuno Monitoring
Screening & Discovery, Research Discovery Peptides, Custom pep-CHIP
Spiked Isotope Peptides, Peptide-in-Plate (96 well plates), pep-CHIP Microarrays
Peptide substrate for kinase, protease and phosphatase profiling in a variety of
Peptide/Protein Identification, Peptide/Protein Quantification, Peptide Protein
Over 10,000 pre-made high quality peptide lyophilized aliquots available for
your immediate experimental needs.
High quality ready-to-go, research grade cosmetic peptides.
For the detection and separate antigen specific CD8+T cell population, suitable
for epitope mapping and immune monitoring.
Peptide pools and libraries in 15mer peptides overlapping by 11 amino acids. 25µg
of >70% purity and ready to use.