[Ac - Lys(Me)16, N - Me - Val18] - beta - Amyloid (16 - 20) - NH2
[Ac - Lys(Me)16, N - Me - Val18] - beta - Amyloid (16 - 20) - NH2
Sequence (1LC):
Ac-K(Me)-L-(N-Me-V)-FF-CONH2
Sequence (3LC):
Ac - Lys(Me) - Leu - (N - Me - Val) - Phe - Phe - CONH2
Price/Unit:
$783
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Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This membrane permeable N-methyl amino acid-containing peptide inhibits b-amyloid 1 to 40 fibrillogenesis. Its structure is remarkably stable to changes in solvent conditions and resists denaturation by heating, changes in pH (from 2.5 to 10.5), and addition of denaturants such as urea and guanindine-HCl. The striking water solubility, in combination with the hydrophobic composition of the peptide, allows the peptide to pass spontaneously through cell membranes.
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Reference/Citations:
- Gordon, D. et al. J. Pept. Res. 60, 37 (2002).
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