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Amyloid Toxicity Inhibitor Peptide 11

Amyloid Toxicity Inhibitor Peptide 11
Sequence (1LC):
RGTFEGKF-CONH2
Sequence (3LC):
NH2 - Arg - Gly - Thr - Phe - Glu - Gly - Lys - Phe - CONH2
Catalog :
13910-01
Unit:
1 mg
Price/Unit:
$579  (For other quantities please Contact Us or call 972-420-8505 (USA) 800-227-0627 (INTL.) or Fax 972.420.0442)
Purity:
>95%
Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
Amyloid toxicity inhibitor peptide 11 is composed of hydrophilic and hydrophobic amino acids. The positively charged unprotected N-terminus allows it to interact with negatively charged C-terminus of b-amyloid 1 to 40. It was shown that this peptide is effective in blocking fibrillization of transmembrane peptide derived from glycophorin A containing a GxMxG motif. Glycophorin sequence can form fibrils with a cross b-structure as in b-amyloid. This peptide inhibits fibrillization by binding to the surface of the beta sheet.
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
M.W.:
940.1 g/mol
Reference/Citations:
  1. Sato, T. et al. Biochem. 45, 5509 (2006).