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β-Amyloid (1 - 42), AMCA - X - labeled

β-Amyloid (1 - 42), AMCA - X - labeled
Sequence (1LC):
AMCA-X-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Sequence (3LC):
AMCA - X - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH
Catalog :
10174-01
Unit:
1 mg
Price/Unit:
$3,375  (For other quantities please Contact Us or call 972-420-8505 (USA) 800-227-0627 (INTL.) or Fax 972.420.0442)
Purity:
>95%
Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This 1-42 native β-amyloid peptide is a component of amyloid plaques that cause Alzheimer''s disease. It is derived from proteolysis of cellular amyloid precursor protein. Synthetic Aβ(1-40) and Aβ(1-42) form amyloid fibrils in vitro that share many features with the amyloid plaques. β-amyloid (1-42) is considered to be a biochemical marker for Alzheimer''s disease. An increasing number of studies suggest that Aβ(1-42) is more pathogenic than the shorter Aβ(1-40) because of its greater tendency to aggregate and precipitate as amyloid.
Storage:
-20°C
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
M.W.:
4842.5
Reference/Citations:
  1. Attems J, et al. (2004)
  2. Acta Neuropathol (Berl) 107, 283-91
  3. Cedazo-Minguez A, et al. (2003)
  4. J Neurochem 87, 1152-64; Mehta PD, et al. (2003)
  5. Neurosci Lett 342, 155-8; Crescenzi O, et al. (2002)
  6. Eur J Biochem 269, 5642-8