8-Oxo-Guanosine, 8-Oxo-rG, contains an oxidized guanosine has been used to facilitate investigations of the structure and activity in DNA lesions. In nature, 8-oxo-dG DNA damage are formed with reactive oxygen species (ROS), and is removed by the base excision repair (BER) mechanism. 8-Oxo-rG oligonucleotide modification is significant in mutagenesis, carcinogenesis, and has been proven useful as a biomarker. Contact Bio-Synthesis for 8-Oxo-rG oligonucleotide modification.
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-20°C To -70°C Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.
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