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8-Oxo-Guanosine, 8-Oxo-rG, contains an oxidized guanosine has been used to facilitate investigations of the structure and activity in DNA lesions. In nature, 8-oxo-dG DNA damage are formed with reactive oxygen species (ROS), and is removed by the base excision repair (BER) mechanism. 8-Oxo-rG oligonucleotide modification is significant in mutagenesis, carcinogenesis, and has been proven useful as a biomarker.

Contact Bio-Synthesis for 8-Oxo-rG oligonucleotide modification.

Product Information

 

Product Name:

8-Oxo-Guanosine, 8-Oxo-rG Oligonucleotide Modification

Category:

Modified RNA Bases

Modification Code:

[8-Oxo-rG]

Chemical Formula:

C10H11N5O8P

Exact Mass:

360.04

Formula Weight:

360.20

Structure:

Bio-Synthesis Inc. Oligo Structure

Purification:

HPLC or PAGE

Delivery Format:

Lyophilized

Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.