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Design and synthesis of peptide-oligonucleotide conjugates as potential artificial ribonucleases

Inna Serpokrylova
12/30/2014
Nucleic Acid Symposium No. 52, 529-530

A series of peptide-oligonucleotide conjugates was synthesized. The peptide fragment was attached to the middle part of DNA sequence. For this purpose the new  amidophosphite dC with linker at C5-position was synthesized.