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DOTA-Peptide Radio Metal Labeling

Yes, Bio-Synthesis offer DOTA-Peptide synthesis and labeling services at various scales and purity. DOTA is the most frequenctly used chelating agent for radio-metal labeling of peptides.  This cyclic chelator 1,4,7,10-tetrazacyclododecane-N,N',N'',N''' -tetraacetic acid (DOTA) contains 4 amino groups and 4 carboxylic groups for coordination of metals, the carboxylic group can be utilized for attachment to amino groups of peptides.

DOTA-Peptide Conjugates

Preparation of peptide-DOTA conjugates can be achieved either by specifically protected building blocks during the peptide synthesis or  via activated esters after the peptide has been prepared. Please provide us peptide sequence and final deliver amount for peptide-DOTA conjugation services.

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Greetings, Researchers,

Please be advised that any information, guidelines, write-ups, and oral/video/graphic content on our website are intended solely as general guidelines.

It is the researcher's sole responsibility to conduct thorough research on the design of products intended for their experiments before submitting
their designs to Biosynthesis for production feasibility review.

Thank you for your understanding.

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