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Peptide Modified with Aminoluciferin

Yes, Bio-Synhtesis provides aminoluciferin peptide modification services. Aminoluciferin (aLuc) is luciferin with its 6-position hydroxyl group substituted with an amino group. This modification allows aLuc to form peptide (amide) bonds with a peptide, while at the same time retaining the transport and bioluminescent properties of luciferin, resulting in a molecule called peptide-aminoluciferin.

Many peptides-aminoluciferin have been used as substrates for luciferase-based (bioluminescence) assays. These substrates offer significant advantages, such as enhanced sensitivity, ease of use, and high throughput screening capacity. Luciferase-based assays are normally 10 to 100-fold more sensitive than comparable fluorescent assays (rhodamine 110, AMC and AFC). For more information, contact us for aminoluciferin peptide synthesis.

 

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Greetings, Researchers,

Please be advised that any information, guidelines, write-ups, and oral/video/graphic content on our website are intended solely as general guidelines.

It is the researcher's sole responsibility to conduct thorough research on the design of products intended for their experiments before submitting
their designs to Biosynthesis for production feasibility review.

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