800.227.0627

What is Lithium Chloride (LiCl) Precipitation?

Lithium Chloride (LiCl) Precipitation: LiCl preferentially precipitates RNA relative to DNA. LiCl precipitation, followed by a 70% ethanol wash, concentrates the RNA and removes most protein, DNA and NTPs. For applications that are very sensitive to DNA contamination, a DNase treatment or additional purification is recommended.