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C-terminus Peptide Methyl Ester Modification

Does Bio-Synthesis provide Peptide Containing C-terminal Methyl Ester Modification?

Yes, Bio-Synthesis provides C-terminus peptide methyl ester modification. Methyl esterification of a peptide converts carboxylic acids, such as those present on the side chains of aspartic (D) and glutamic acid (E) as well as the free carboxyl terminus, to their corresponding methyl ester.  Modified C-terminal methyl ester modified peptides can be used as tools for the study of protein prenylation and other structurally related biological process. The presence of the alkyl ester at the C-terminus enhance peptide permeability through cell membrane since this modification increase hydrophobicity of the peptide. Contact us for Peptide C-terminal Methyl Ester Modifcation.