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dSpacer also known as an abasic site, tetrahydrofuran (THF) can be used to inert to a single base space into a DNA oligonucleotide. This absic base modification often used to exame DNA damage and repair that occur naturally through depurination or other mechanisms.

Product Information

 

Product Name:

dSpacer (Abasic Furan) Oligonucleotide Modification

Alternate Name:

Abasic Furan

Category:

spacer, abasic site, Tetrahydrofuran

Modification Code:

dSpacer

Chemical Formula:

C5H9O5P

Exact Mass:

180.02

Formula Weight:

180.10

m/z:

180.02 (100.0%), 181.02 (5.6%), 182.02 (1.0%)

Elemental Analysis:

C, 33.35; H, 5.04; O, 44.42; P, 17.20

Structure:

Bio-Synthesis Inc. Oligo Structure

Purification:

HPLC or PAGE

Delivery Format:

Lyophilized

Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.