Choose from dual-labeled qPCR probes, molecular beacons, FRET designs, MGB and Affinity-Enhanced chemistries, PNA FISH, branched DNA (bDNA) amplifiers, and complete MERFISH encoding/readout sets. We provide fast design support, RUO → GMP-like manufacturing, and full QC.
We manufacture custom probes for qPCR, ISH/FISH, and spatial transcriptomics. Every project can be tuned for Tm, length, mismatch discrimination, dye/quencher pairing, and signal-to-noise. Options include dark quenchers, ratiometric FRET, minor groove binders (MGB), LNA/BNA/cEt upgrades, PNA backbones, disulfide-cleavable linkers for release, and dye balancing for multi-round imaging.
Nine core offerings, presented as quick-scan cards. Click in to jump to details.
5′-reporter / 3′-quencher probes for hydrolysis assays with high S/N, fast cycling and robust multiplexing. Learn more
Reporter/quencher libraries, internal quenchers, short-amplicon tuning, and multiplex kits. See options
MGB tail elevates Tm for short probes, improving SNP specificity in qPCR. Why MGB
Stem-loop probes that fluoresce only upon hybridization—great for multiplex & live-cell. Beacon guide
Donor–acceptor pairs for distance-dependent, drift-resistant readouts - ideal for low-copy transcripts in tissue FRET formats
Error-robust barcodes and dye-balanced readouts for 10–10,000+ targets. MERFISH details
Branched DNA trees deliver high brightness at low background. Amplifier sets
Peptide-nucleic acid backbones enable strong, salt-tolerant binding for rapid ID. PNA in FISH
Locked/bridged nucleic acids and 2′-mods shorten length and heighten discrimination. Upgrade paths
FAM • HEX • VIC • TET • ROX • Cy3 • Cy5 • ATTO dyes • Quenchers: BHQ-1/2/3, IAbRQSp/3IABkFQ, QSY series. Ask about dye balancing for multiplex panels.
Tip: For short SNP assays, pair MGB or LNA with a dark quencher for sharp ΔRn.
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